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PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of this

PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of this

Name: PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of this
Brand: nyherosfund.org
SKU: 10342738101
Price: 111.00 USD
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Rating: 4.7029000000000005 (27 reviews)

SKU: 10342738101

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PERK(Phospho Thr981) Polyclonal Antibody, 20ul Bottle-Top Dispenser An important paralog of thisThe protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in

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Description

An important paralog of this gene is BTF3

It is ubiquitous

and is implicated in the transcriptional regulation of Hox genes and cytokines

Mutations in this gene cause the autosomal dominant disorder

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