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Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables |cofactor:Binds 1 Fe(3+) ion per

SKU: 10360402406

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Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables |cofactor:Binds 1 Fe(3+) ion perThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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|cofactor:Binds 1 Fe(3+) ion per subunit

Some transcripts contain a differentially methylated region (DMR) at their 5' exons| and this DMR is commonly found in imprinted genes and correlates with transcript expression

Wiskott-Aldrich syndrome is a disease of the immune system

thereby contributing to the inotropic response elicited in heart by beta-agonists

Rb(Phospho Ser608) Polyclonal Antibody, 20ul Liquid Storage Consumables |cofactor:Binds 1 Fe(3+) ion perThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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