HNF1A Polyclonal Antibody, 20ul Biomatrix The enzyme is under long

The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA

The protein encoded by this gene contains a formin homology 2 domain and has high sequence identity to the mouse Wbp3 protein

It has been shown to associate with an actin nucleation core Arp2/3 complex while enhancing actin polymerization in vitro

Belongs to the AP-2 family

HNF1A Polyclonal Antibody, 20ul Biomatrix The enzyme is under longThe protein encoded by this gene is a transcription factor required for the expression of several liver specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5' GTTAATNATTAAC 3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. Alternative splicing results in multiple transcript variants encoding different