PTTG1/2/3 Polyclonal Antibody, 50ul Gloves reticuloendothelial system

reticuloendothelial system

sequestering them in the cytoplasm and reducing their binding to DNA

It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs

They encode hybrid proteins that have N-terminal Golli aa sequence linked to MBP aa sequence

PTTG1/2/3 Polyclonal Antibody, 50ul Gloves reticuloendothelial systemPituitary tumor transforming 1 is a homolog of yeast securin proteins, which prevent separins from promoting sister chromatid separation. It is an anaphase promoting complex (APC) substrate that associates with a separin until activation of the APC. PTTG1 product has transforming activity in vitro and tumorigenic activity in vivo, and the gene is highly expressed in various tumors. PTTG1 contains 2 PXXP motifs, which are required for its transforming