ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment SP3 (Sp3 transcription factor) belongs

SP3 (Sp3 transcription factor) belongs to a family of Sp1 related genes that encode transcription factors that regulate transcription by binding to consensus GC- and GT-box regulatory elements in target genes

Several alternatively spliced transcript variants of FKRP have been described

The enzyme comprises a 110 kD catalytic subunit and a regulatory subunit of either 85

Alternative splicing results in multiple transcript variants| at least one of which encodes an isoform that is proteolytically processed

ATM Rabbit Polyclonal Antibody, 50ul[BT-AP06560] In vitro Assessment SP3 (Sp3 transcription factor) belongsThe protein encoded by this gene belongs to the PI3 PI4 kinase family. This protein is an important cell cycle checkpoint kinase that phosphorylates; thus, it functions as a regulator of a wide variety of downstream proteins, including tumor suppressor proteins p53 and BRCA1, checkpoint kinase CHK2, checkpoint proteins RAD17 and RAD9, and DNA repair protein NBS1. This protein and the closely related kinase ATR are thought to be master controllers of