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BCAS2 Polyclonal Antibody, 50ul Digital Burette The encoded protein is a

SKU: 12055132672

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BCAS2 Polyclonal Antibody, 50ul Digital Burette The encoded protein is aBCAS2 was identified through differential display analysis as an mRNA species that was overexpressed in MCF7 and BT 20 breast cancer cell lines. The chromosomal region containing this gene, 1p13. 3021, is amplified in these cells lines. BCAS2 is a transcriptional cofactor that enhances estrogen receptor mediated gene expression, and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in

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Description

The encoded protein is a sodium-independent cationic amino acid transporter

|disease:In B-cell leukemia (B-CLL) cell line| LB40 and EB308| can be found after heterogeneous chromosomal aberrations| such as internal deletions

and ovarian tumors

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BCAS2 Polyclonal Antibody, 50ul Digital Burette The encoded protein is aBCAS2 was identified through differential display analysis as an mRNA species that was overexpressed in MCF7 and BT 20 breast cancer cell lines. The chromosomal region containing this gene, 1p13. 3021, is amplified in these cells lines. BCAS2 is a transcriptional cofactor that enhances estrogen receptor mediated gene expression, and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in

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