MRCKBeta Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection Studies of the mouse counterpart

Studies of the mouse counterpart suggest that this receptor may also mediate adrenocorticotropic hormone response as well as fever generation in response to exogenous and endogenous stimuli

ADGRE2 encodes a member of the class B seven-span transmembrane (TM7) subfamily of G-protein coupled receptors

extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins

The protein appears to be located in both the cytoplasm and nucleus but not in the nucleolus

MRCKBeta Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection Studies of the mouse counterpartCDC42BPB encodes a member of the serine threonine protein kinase family. Serine threonine protein kinase MRCK beta contains a Cdc42 Rac binding p21 binding domain resembling that of PAK kinase. The kinase domain of this protein is most closely related to that of myotonic dystrophy kinase related ROK. Studies of the similar gene in rat suggested that this kinase may act as a downstream effector of Cdc42 in cytoskeletal reorganization.