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CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection as it contains characteristic adjacent

SKU: 12486615031

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CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection as it contains characteristic adjacentThis gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological

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Description

as it contains characteristic adjacent cysteine residues

the full-length nature of only some have been determined

Mutations in this gene cause Gitelman syndrome| a disease similar to Bartter's syndrome| that is characterized by hypokalemic alkalosis combined with hypomagnesemia| low urinary calcium| and increased renin activity associated with normal blood pressure

Interacts with CRSP2 and CRSP6

CRMP-2(Phospho Thr514) Polyclonal Antibody, 20ul Cell Transfection as it contains characteristic adjacentThis gene encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo and hetero tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. This gene has been implicated in multiple neurological

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