Thioredoxin Polyclonal Antibody, 20ul Vacuum Filter POLQ-mediated MMEJ may be required

POLQ-mediated MMEJ may be required to promote the survival of cells with a compromised HR repair pathway

and inhibiting its expression partially suppresses p53-induced apoptosis

but forms heteromultimers with several other subfamily members

under certain conditions

Thioredoxin Polyclonal Antibody, 20ul Vacuum Filter POLQ-mediated MMEJ may be requiredThe protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene.