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S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergent

SKU: 12811219985

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SEK162.00 SEK207.00

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S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergentThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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Description

ARF4 is the most divergent member of the human ARFs

An alternatively spliced transcript variant of this gene has been reported| however| its full length nature is not known

Cdc45 is a member of the highly conserved multiprotein complex including Cdc6/Cdc18

This gene encodes a protein which contains a several motifs including a ski homology region and a SET-binding region in addition to three nuclear localization signals

S12A1 Rabbit Polyclonal Antibody, 50ul Primary Antibodies ARF4 is the most divergentThis gene encodes a kidney specific sodium potassium chloride cotransporter that is expressed on the luminal membrane of renal epithelial cells of the thick ascending limb of Henle's loop and the macula densa. It plays a key role in concentrating urine and accounts for most of the NaCl resorption. It is sensitive to such diuretics as furosemide and bumetanide. Some Bartter like syndromes result from defects in this gene. Alternative splicing results

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