FRPD2 Rabbit Polyclonal Antibody, 20ul Cell Senescence accessory subunit plays a role

accessory subunit plays a role in regulating the activity of DNA polymerase delta through interactions with other subunits and the processivity cofactor proliferating cell nuclear antigen (PCNA)

Several pseudogenes of this gene have been identified

enzyme regulation:Appears to be activated by multiple phosphorylations on threonine and serine residues

Three splice variants that encode different isoforms have been identified for CTTN

FRPD2 Rabbit Polyclonal Antibody, 20ul Cell Senescence accessory subunit plays a roleThis gene encodes a peripheral membrane protein and is located in a region of chromosome 10q that contains a segmental duplication. This copy of the gene is full length and is in the telomeric duplicated region. Two other more centromerically proximal copies of the gene are partial and may represent pseudogenes. This full length gene appears to function in the establishment and maintenance of cell polarization. The protein is recruited to cell cell