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IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domains

SKU: 13550925364

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IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domainsIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants

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Description

Contains 10 EGF-like domains

SIGLEC5 encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family

and it has also been found as part of a contiguous gene deletion associated with craniofrontonasal syndrome

This gene maps in a region that contains the BRCA1 locus which confers susceptibility to breast and ovarian cancer

IGFBP7 Polyclonal Antibody, 50ul Biochemical Reagents Contains 10 EGF-like domainsIGFBP7 encodes a member of the insulin like growth factor (IGF) binding protein (IGFBP) family. IGFBPs bind IGFs with high affinity, and regulate IGF availability in body fluids and tissues and modulate IGF binding to its receptors. This protein binds IGF I and IGF II with relatively low affinity, and belongs to a subfamily of low affinity IGFBPs. It also stimulates prostacyclin production and cell adhesion. Alternatively spliced transcript variants

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