Histone H2B (Acetyl Lys121) Rabbit Polyclonal Antibody, 100ul Deep Well Plates APP (amyloid beta precursor protein)

APP (amyloid beta precursor protein) encodes a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides

and a 40-kD subunit that is a member of the cytokine receptor family

This cytoplasmic protein contains seven WD repeats and an AF-2 domain which function by recruiting coregulatory molecules and in transcriptional activation

Mutations in this gene have been linked to autosomal dominant and recessive forms of nephrogenic diabetes insipidus

Histone H2B (Acetyl Lys121) Rabbit Polyclonal Antibody, 100ul Deep Well Plates APP (amyloid beta precursor protein)Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A H2B H3 and H4). The chromatin fiber is further compacted through the interaction of a linker histone H1 with the DNA between the nucleosomes to form higher order chromatin structures. This