NGB Polyclonal Antibody, 100ul Apoptosis & Autophagy SLCO1B1 encodes a liver-specific member

SLCO1B1 encodes a liver-specific member of the organic anion transporter family

inhibits VAV1 activation upon TCR engagement and imposes a requirement for CD28 costimulation for proliferation and IL-2 production

Mutations in this gene result in autosomal dominant hereditary thrombophilia

Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I)

NGB Polyclonal Antibody, 100ul Apoptosis & Autophagy SLCO1B1 encodes a liver-specific memberThis gene encodes an oxygen binding protein that is distantly related to members of the globin gene family. It is highly conserved among other vertebrates. It is expressed in the central and peripheral nervous system where it may be involved in increasing oxygen availability and providing protection under hypoxic ischemic conditions.