IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody, 100ul Protein Expression some protein-coding and some non-protein

some protein-coding and some non-protein coding

including small cell lung carcinoma and renal cell carcinoma

Alternative splicing results in multiple transcripts encoding different isoforms

PSCA includes a polymorphism that results in an upstream start codon in some individuals

IGF-IR(Phospho Tyr1165/Y1166) Polyclonal Antibody, 100ul Protein Expression some protein-coding and some non-proteinThis receptor binds insulin like growth factor with a high affinity. It has tyrosine kinase activity. The insulin like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have