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PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediated

SKU: 14753547072

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PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediatedThe protein kinase D2 encoded by PRKD2 belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants

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Description

Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle

Members of this family are sodium and chloride dependent neurotransmitter transporters

L-tryptophan and L-phenylalanine may act as the physiologic ligands of the encoded protein

and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum

PKD2 Polyclonal Antibody, 100ul[BT-AP07231] Transporters Required for poly-ubiquitination and proteasome-mediatedThe protein kinase D2 encoded by PRKD2 belongs to the protein kinase D (PKD) family of serine threonine protein kinases. This kinase can be activated by phorbol esters as well as by gastrin via the cholecystokinin B receptor (CCKBR) in gastric cancer cells. It can bind to diacylglycerol (DAG) in the trans Golgi network (TGN) and may regulate basolateral membrane protein exit from TGN. Alternative splicing results in multiple transcript variants

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