TH Polyclonal Antibody, 50ul[BT-AP08991] Cell Labeling & Imaging Affected individuals display mottled pigmentation

Affected individuals display mottled pigmentation

the encoded protein was initially isolated based on its ability to inhibit v-Ras transformation

This gene encodes a member of the protein kinase C (PKC) family of serine/threonine protein kinases

Mutations affecting this gene are the cause of autosomal recessive hyper-IgM immunodeficiency type 3 (HIG

TH Polyclonal Antibody, 50ul[BT-AP08991] Cell Labeling & Imaging Affected individuals display mottled pigmentationTyrosine 3 monooxygenase encoded by TH is involved in the conversion of tyrosine to dopamine. It is the rate limiting enzyme in the synthesis of catecholamines, hence plays a key role in the physiology of adrenergic neurons. Mutations in this gene have been associated with autosomal recessive Segawa syndrome. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.