FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology It is also a candidate

It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome

This gene encodes the smallest subunit of DNA polymerase delta

May be a negative regulator of NF-kappa-B and p53-mediated gene transcription

It may play a role in the regulation of phospholipid turnover as well as in protection against oxidative injury

FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology It is also a candidateMembers of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004