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Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence not all variants have been

SKU: 16111469092

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Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence not all variants have beenINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited

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Description

not all variants have been fully characterized

Interacts with the Axin complex

can result in hypercalcemia and kidney stones

It has also been reported to be highly expressed in thyroids of patients with Graves disease

Insulin R Polyclonal Antibody, 50ul[BT-AP04565] Cell Senescence not all variants have beenINSR encodes a member of the receptor tyrosine kinase family of proteins. Insulin receptor is proteolytically processed to generate alpha and beta subunits that form a heterotetrameric receptor. Binding of insulin or other ligands to this receptor activates the insulin signaling pathway, which regulates glucose uptake and release, as well as the synthesis and storage of carbohydrates, lipids and protein. Mutations in this gene underlie the inherited

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