WIPI2(Phospho-Ser413) Rabbit Polyclonal Antibody, 100ul Pipette Holder Proteolytic cleavage is important for

Proteolytic cleavage is important for targeting of the proteins to the NPC

|Associates with IL12B to form the IL-23 interleukin| an heterodimeric cytokine which functions in innate and adaptive immunity

The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase

This gene encodes a member of the anoctamin family of transmembrane proteins

WIPI2(Phospho-Ser413) Rabbit Polyclonal Antibody, 100ul Pipette Holder Proteolytic cleavage is important forWD40 repeat proteins are key components of many essential biologic functions. They regulate the assembly of multiprotein complexes by presenting a beta propeller platform for simultaneous and reversible protein protein interactions. Members of the WIPI subfamily of WD40 repeat proteins such as WIPI2 have a 7 bladed propeller structure and contain a conserved motif for interaction with phospholipids (Proikas Cezanne et al. 2004