Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing Knockout studies in mice suggest

Knockout studies in mice suggest that this gene plays a critical role in regulating myocyte apoptosis

The gene is highly polymorphic in the human population

This gene encodes a glutamate decarboxylase that catalyzes the deglutamylation of polyglutamylated proteins

while the carboxy-terminal region is protease sensitive

Phospho-Artemis (S516) Polyclonal Antibody, 50ul Gene Editing Knockout studies in mice suggestDCLRE1C encodes a nuclear protein that is involved in V(D)J recombination and DNA repair. The encoded protein has single strand specific 5' 3' exonuclease activity; it also exhibits endonuclease activity on 5' and 3' overhangs and hairpins. The protein also functions in the regulation of the cell cycle in response to DNA damage. Mutations in DCLRE1C can cause Athabascan type severe combined immunodeficiency (SCIDA) and Omenn syndrome. Alternative