Phospho-Amyloid-Beta (T743) Polyclonal Antibody, 50ul Centrifuges The encoded protein may inhibit

The encoded protein may inhibit chemotaxis and invasion and thereby attenuate metastasis in malignant melanomas

It appears to function as a E3 ubiquitin-ligase and ubiqutinates itself to regulate its subcellular localization

with weak expression in several other tissues tested

This may be accomplished through interaction with p21-activated kinase

Phospho-Amyloid-Beta (T743) Polyclonal Antibody, 50ul Centrifuges The encoded protein may inhibitAPP encodes a cell surface receptor and transmembrane precursor protein (amyloid beta precursor protein) that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1 TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. In addition, two of the peptides are