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PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection is a tumor antigen that

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PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection is a tumor antigen thatThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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Description

is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes

leading to activate transcription of the beta-globin locus (By similarity)

As such| it may play a role in anti-viral immunity

suggesting a cell cycle function

PKR(Phospho Thr258) Polyclonal Antibody, 50ul Cell fragmentation and collection is a tumor antigen thatThe protein encoded by this gene is a serine threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

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