ZNF420 Polyclonal Antibody, 100ul Peptide Library Nkx2-6 may play a role

Nkx2-6 may play a role in both pharyngeal and cardiac embryonic development

Many of the subunits belong to a family called nucleoporins (Nups)

Regulates the expression of specific CREB-activated genes such as the steroidogenic gene

although the full-length nature of only two has been determined

ZNF420 Polyclonal Antibody, 100ul Peptide Library Nkx2-6 may play a roleZinc finger protein 420 encoded by ZNF420 is a KRAB type zinc finger protein that negatively regulates p53 mediated apoptosis. Under stress conditions, the encoded protein is phosphorylated by ATM and dissociates from p53, which activates p53 and initiates apoptosis.