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Neuregulin-3 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Mutations in this gene result

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Neuregulin-3 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Mutations in this gene resultNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to

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Description

Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions

and acts as an autocrine factor to induce apoptosis in endothelial cells

Key genes for eye color and hair color also map to chromosome 19

The clinical implications of this receptor are unknown

Neuregulin-3 Polyclonal Antibody, 50ul Cellular Cultivation & Health Management Mutations in this gene resultNRG3 (neuregulin 3) is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 members of the epidermal growth factor receptor family. Ligand binding activates intracellular signaling cascades and the induction of cellular responses including proliferation, migration, differentiation, and survival or apoptosis. This gene encodes neuregulin 3 (NRG3). NRG3 has been shown to

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