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RANKL Polyclonal Antibody, 50ul[BT-AP07786] Molecular Sciences The protein encoded by PTPRC

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RANKL Polyclonal Antibody, 50ul[BT-AP07786] Molecular Sciences The protein encoded by PTPRCThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.

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Description

The protein encoded by PTPRC (protein tyrosine phosphatase

mature peptide and a C-terminal propeptide

These factors form heterodimers with Mad proteins and play a role in proliferation

designated FX in humans (MIM 137020)

RANKL Polyclonal Antibody, 50ul[BT-AP07786] Molecular Sciences The protein encoded by PTPRCThis gene encodes a member of the tumor necrosis factor (TNF) cytokine family which is a ligand for osteoprotegerin and functions as a key factor for osteoclast differentiation and activation. This protein was shown to be a dentritic cell survival factor and is involved in the regulation of T cell dependent immune response. T cell activation was reported to induce expression of this gene and lead to an increase of osteoclastogenesis and bone loss.

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