PAPP1 Polyclonal Antibody, 50ul Rotator The protein encoded by this

The protein encoded by this gene is a transcriptional repressor thought to negatively regulate MYC function

also known as neuritis with brachial predilection

These family members contain multiple N-terminal leucine-rich repeats| in addition to a C-terminal calponin homology domain| a type of domain that mediates interactions with actin filaments

This gene encodes a major cytoplasmic protein which is the only known constituent common to submembranous plaques of both desmosomes and intermediate junctions

PAPP1 Polyclonal Antibody, 50ul Rotator The protein encoded by thisThis gene encodes a secreted metalloproteinase which cleaves insulin like growth factor binding proteins (IGFBPs). It is thought to be involved in local proliferative processes such as wound healing and bone remodeling. Low plasma level of this protein has been suggested as a biochemical marker for pregnancies with aneuploid fetuses.