Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression subcellular localization

subcellular localization

There are multiple components involved in the NER pathway| including Xeroderma pigmentosum (XP) A-G and V| Cockayne syndrome (CS) A and B| and trichothiodystrophy (TTD) group A| etc

It was suggested that inefficient splicing of this first intron

Present in T-cells but not B-cells (at protein level)

Btk Polyclonal Antibody, 100ul[BT-AP01005] Insect Expression subcellular localizationThe protein (Bruton tyrosine kinase) encoded by BTK plays a crucial role in B cell development. Mutations in this gene cause X linked agammaglobulinemia type 1, which is an immunodeficiency characterized by the failure to produce mature B lymphocytes, and associated with a failure of Ig heavy chain rearrangement. Alternative splicing results in multiple transcript variants encoding different isoforms.