TNKS2 Polyclonal Antibody, 20ul Purification PTM:The disulfide bond may lock

PTM:The disulfide bond may lock the enzyme in a closed conformation under oxidized conditions

with possible mental retardation

Unlike other elastases

Core component of multiple SCF-like ECS (Elongin-Cullin 2/5-SOCS-box protein) E3 ubiquitin-protein ligase complexes

TNKS2 Polyclonal Antibody, 20ul Purification PTM:The disulfide bond may lockCatalytic activity: NAD(+) + (ADP D ribosyl)(n) acceptor = nicotinamide + (ADP D ribosyl)(n+1) acceptor.,May regulate vesicle trafficking and modulate the subcellular distribution of SLC2A4 GLUT4 vesicles. Has PARP activity and can modify TRF1, and thereby contribute to the regulation of telomere length.,PTM: ADP ribosylated ( auto).,Contains 1 PARP catalytic domain.,Contains 1 SAM (sterile alpha motif) domain.,Contains 15 ANK repeats.,subcellular