F110C Rabbit Polyclonal Antibody, 50ul Peptide Modification The N-terminal region is required

The N-terminal region is required for nuclear localization and the C-terminal region mediates transcriptional activity

The encoded protein| which is insoluble and found both in the nucleus and in the cytoplasm| can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits

The encoded protein acts as a repressor when not bound to Notch proteins and an activator when bound to Notch proteins

The encoded preproprotein is proteolytically processed to generate light and heavy chains that associate through disulfide linkages to form a subunit of the alpha-IIb/beta-3 integrin cell adhesion receptor

F110C Rabbit Polyclonal Antibody, 50ul Peptide Modification The N-terminal region is required