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Egr-2 Polyclonal Antibody, 50ul Molecular Biology It is selectively expressed in

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Egr-2 Polyclonal Antibody, 50ul Molecular Biology It is selectively expressed inEarly growth response 1 encoded by EGR1 belongs to the EGR family of C2H2 type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene.

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Description

It is selectively expressed in reactive stromal fibroblasts of epithelial cancers

mediating cellular proliferation

It is found among several proteins that bind directly to retinoblastoma protein| which regulates cell proliferation

subunit:Binds to SLC9A3R2 via the PDZ motif at the plasma membrane

Egr-2 Polyclonal Antibody, 50ul Molecular Biology It is selectively expressed inEarly growth response 1 encoded by EGR1 belongs to the EGR family of C2H2 type zinc finger proteins. It is a nuclear protein and functions as a transcriptional regulator. The products of target genes it activates are required for differentitation and mitogenesis. Studies suggest this is a cancer suppressor gene.

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