PLB Polyclonal Antibody, 50ul Thermal Control The encoded protein mediates facilitated
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PLB Polyclonal Antibody, 50ul Thermal Control The encoded protein mediates facilitatedThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the
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