Dysferlin Polyclonal Antibody, 50ul ADME Upregulated expression of this gene

Upregulated expression of this gene in astroglial cells upon exposure to lipopolysaccharides suggests a function for the encoded protein in the brain

and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release

FLRTs may function in cell adhesion and/or receptor signalling

Low expression in heart

Dysferlin Polyclonal Antibody, 50ul ADME Upregulated expression of this geneThe protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin 3, a skeletal muscle membrane protein which is important in the