HDAC4 Polyclonal Antibody, 50ul Shakers Contains 1 SOCS box domain

Contains 1 SOCS box domain

GO annotations related to this gene include hydrolase activity

but isoform 2 lacking this C-terminal region is also tyrosine-phosphorylated

naturally-occuring variation in the promoter and 5' non-coding and coding regions of this gene may show statistically-significant association with mental illness and behavioral disorders

HDAC4 Polyclonal Antibody, 50ul Shakers Contains 1 SOCS box domainHistones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 4 encoded by HDAC4 belongs to class II of the histone deacetylase acuc apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. Histone deacetylase 4 does not