Rat Sterol Regulatory Element-binding Protein 1C, SREBP-1C ELISA Kit, 96T Enzyme Activity Assays PubMed: 30356214)

PubMed: 30356214)

The encoded protein contains a highly conserved J domain of about 70 amino acids with a characteristic His-Pro-Asp (HPD) motif and may regulate the activity of binding immunoglobulin protein by stimulating ATPase activity

Binds specifically and cooperatively to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3') and activates transcription in vivo in a cell-specific manner

Mutations in this gene cause primary ciliary dyskinesia 1| a disease arising from dysmotility of motile cilia and sperm

Rat Sterol Regulatory Element-binding Protein 1C, SREBP-1C ELISA Kit, 96T Enzyme Activity Assays PubMed: 30356214)