PTEN (Acetyl Lys402) Polyclonal Antibody, 100ul Centrifuges The encoded protein binds only

The encoded protein binds only GTP but has no GTPase activity

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins

consists of two heavy chains and four light chains

mice in which this gene has been inactivated exhibit abnormal gene expression in urinary tract smooth muscle cell precursors and kidney defects including hydronephrosis

PTEN (Acetyl Lys402) Polyclonal Antibody, 100ul Centrifuges The encoded protein binds onlyPTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by PTEN is a phosphatidylinositol 3,4,5 trisphosphate 3 phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases,phosphatase and tensin homolog preferentially dephosphorylates