PIGA Polyclonal Antibody, 50ul Erlenmeyer Flasks Caspases mediate cellular apoptosis through

Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates

Expression is frequently lower in intestinal-type gastric cancer

This gene is thought to be involved in CNS development

Mutations in this gene are associated with infantile-onset multisystem autoimmune disease and hyper-immunoglobulin E syndrome

PIGA Polyclonal Antibody, 50ul Erlenmeyer Flasks Caspases mediate cellular apoptosis throughThis gene encodes a protein required for synthesis of N acetylglucosaminyl phosphatidylinositol (GlcNAc PI), the first intermediate in the biosynthetic pathway of GPI anchor. The GPI anchor is a glycolipid found on many blood cells and which serves to anchor proteins to the cell surface. Paroxysmal nocturnal hemoglobinuria, an acquired hematologic disorder, has been shown to result from mutations in this gene. Alternate splice variants have been