PDE2A Polyclonal Antibody, 20ul Liquid Handling ＆Storage The mRNA and the protein

The mRNA and the protein of this gene are upregulated by wildtype p53 and overexpression of this gene inhibits tumor cell growth

Interacts also with HNRPL and SLM1/KHDRBS2 (By similarity)

This gene encodes a member of the peptidase T1A family| that is a 20S core alpha subunit

May be involved in the structural organization of the nucleus and in the post-mitotic nuclear assembly

PDE2A Polyclonal Antibody, 20ul Liquid Handling ＆Storage The mRNA and the proteinalternative products: Additional isoforms seem to exist. Experimental confirmation may be lacking for some isoforms,Catalytic activity: Nucleoside 3',5' cyclic phosphate + H(2)O = nucleoside 5' phosphate.,Hydrolyzes both cyclic AMP (cAMP) and cyclic GMP (cGMP).,Belongs to the cyclic nucleotide phosphodiesterase family.,Contains 2 GAF domains.,subunit: Homodimer.,tissue specificity: Expressed in brain and to a lesser extent in heart, placenta, lung,