Ku-80 Monoclonal Antibody, 50ul Metabolic enzymes tool compounds SHC1 encodes three main isoforms

SHC1 encodes three main isoforms that differ in activities and subcellular location

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belongs to the UPF0378 family

Suppresses Src-dependent tyrosine phosphorylation and activation of PDPK1 and its downstream signaling

Ku-80 Monoclonal Antibody, 50ul Metabolic enzymes tool compounds SHC1 encodes three main isoformsThe protein encoded by this gene is the 80 kilodalton subunit of the Ku heterodimer protein which is also known as ATP dependant DNA helicase II or DNA repair protein XRCC5. Ku is the DNA binding component of the DNA dependent protein kinase, and it functions together with the DNA ligase IV XRCC4 complex in the repair of DNA double strand break by non homologous end joining and the completion of V(D)J recombination events. This gene functionally