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RELN Polyclonal Antibody, 50ul Vortex Mixer The encoded protein| whose degradation

SKU: 23661859874

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RELN Polyclonal Antibody, 50ul Vortex Mixer The encoded protein| whose degradationThis gene encodes a large secreted extracellular matrix protein thought to control cell cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two

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Description

The encoded protein| whose degradation is induced in a proteasome-dependent manner by MDM2| is a membrane-bound protein that has been shown to associate with EPS15| LNX1| and NOTCH1

It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1

Belongs to the CLASP family

The cytoplasmic peripheral membrane protein encoded by EZR (ezrin) functions as a protein-tyrosine kinase substrate in microvilli

RELN Polyclonal Antibody, 50ul Vortex Mixer The encoded protein| whose degradationThis gene encodes a large secreted extracellular matrix protein thought to control cell cell interactions critical for cell positioning and neuronal migration during brain development. This protein may be involved in schizophrenia, autism, bipolar disorder, major depression and in migration defects associated with temporal lobe epilepsy. Mutations of this gene are associated with autosomal recessive lissencephaly with cerebellar hypoplasia. Two

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