SP6 Polyclonal Antibody, 100ul Enzymes Mutations in this gene are

Mutations in this gene are associated with atypical hemolytic uremic syndrome and age-related macular degeneration in human patients

This antimicrobial gene is one of several chemokine genes clustered on the q-arm of chromosome 17

The protein encoded by this gene plays a crucial role in B-cell development

A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology

SP6 Polyclonal Antibody, 100ul Enzymes Mutations in this gene areSP6 belongs to a family of transcription factors that contain 3 classical zinc finger DNA binding domains consisting of a zinc atom tetrahedrally coordinated by 2 cysteines and 2 histidines (C2H2 motif). These transcription factors bind to GC rich sequences and related GT and CACCC boxes (Scohy et al., 2000