PLB Polyclonal Antibody, 100ul Immunology It is localized to the

It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region

Expression of this gene is almost exclusively in the brain

and it therefore likely functions in spermatid formation

member 2 (NR1A2)

PLB Polyclonal Antibody, 100ul Immunology It is localized to theThe protein encoded by PLN (phospholamban)is found as a pentamer and is a major substrate for the cAMP dependent protein kinase in cardiac muscle. The encoded protein is an inhibitor of cardiac muscle sarcoplasmic reticulum Ca(2+) ATPase in the unphosphorylated state, but inhibition is relieved upon phosphorylation of the protein. The subsequent activation of the Ca(2+) pump leads to enhanced muscle relaxation rates, thereby contributing to the