FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 100ul Microplate Mixer reducing fatigue and offering a

reducing fatigue and offering a smoother

Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms

The aberrant regulation of this gene contributes to tumor cell invasion and metastasis

The encoded product is primarily responsible for glycine synthesis

FoxO4 (Acetyl Lys407) Rabbit Polyclonal Antibody, 100ul Microplate Mixer reducing fatigue and offering adisease: A chromosomal aberration involving FOXO4 is found in acute leukemias. Translocation t(X; 11)(q13; q23) with MLL HRX. The result is a rogue activator protein. Transcription factor involved in the regulation of the insulin signaling pathway. Binds to insulin response elements (IREs) and can activate transcription of IGFBP1. Down regulates expression of HIF1A and suppresses hypoxia induced transcriptional activation of HIF1A modulated genes.