FAK Monoclonal Antibody, 50ul[BT-MCA0525] Cellular Function Assays Mutations in this gene have

Mutations in this gene have been associated with autosomal recessive spondylocostal dysostosis 3

EXPAND1/MUM1 accumulates at sites of DNA double strand breaks through direct interaction with DNA repair factor 53BP1

and is thought to be a mediator of EBV effects on B lymphocytes

Treated for optimal cell growth and equipped with a vent cap to ensure proper gas exchange

FAK Monoclonal Antibody, 50ul[BT-MCA0525] Cellular Function Assays Mutations in this gene haveThis gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal