Human Interleukin-1 Receptor-associated Kinase 1, IRAK1 ELISA Kit, 96T Molecular Weight Markers Binds to the proximal sequence

Binds to the proximal sequence element (PSE)

PubMed: 10684867

The protein encoded by PIGY (phosphatidylinositol glycan anchor biosynthesis class Y)is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI)

which may facilitate the expression of gut-homing and adhesion molecules on T-cells and the conversion of CD4+ T-cells into CD4+ CD8+ T-cells (By similarity)

Human Interleukin-1 Receptor-associated Kinase 1, IRAK1 ELISA Kit, 96T Molecular Weight Markers Binds to the proximal sequenceSerine threonine protein kinase that plays a critical role in initiating innate immune response against foreign pathogens. Involved in Toll like receptor (TLR) and IL 1R signaling pathways. Is rapidly recruited by MYD88 to the receptor signaling complex upon TLR activation. Association with MYD88 leads to IRAK1 phosphorylation by IRAK4 and subsequent autophosphorylation and kinase activation. Phosphorylates E3 ubiquitin ligases Pellino proteins