Cathepsin D Polyclonal Antibody, 20ul[BT-AP01238] sgRNA customized design Defects in this gene cause

Defects in this gene cause familial adenomatous polyposis (FAP)

called muscle acylphosphatase and erythrocyte acylphosphatase on the basis of their tissue localization

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is located in the mitochondria and expressed in extra-hepatic tissues

Cathepsin D Polyclonal Antibody, 20ul[BT-AP01238] sgRNA customized design Defects in this gene causeCTSD encodes a member of the A1 family of peptidases. The encoded preproprotein is proteolytically processed to generate multiple protein products. These products include the cathepsin D light and heavy chains, which heterodimerize to form the mature enzyme. This enzyme exhibits pepsin like activity and plays a role in protein turnover and in the proteolytic activation of hormones and growth factors. Mutations in this gene play a causal role in