IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 50ul Funnels It is an essential component

It is an essential component of the transcription factor TFIIH

The encoded protein appears to be part of the connector linking these two components and may be involved in transmission of conformational changes or proton conductance

|PTM:Phosphorylation at Ser-554 by PKB is required for interaction with ITGB1| export of ITGB1 from recycling endosomes to the cell surface and ITGB1-dependent cell migration

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IRS-1(Phospho-Ser612) Rabbit Polyclonal Antibody, 50ul Funnels It is an essential componentThis gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance.