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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis Multiple transcript variants encoding different

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Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis Multiple transcript variants encoding differentThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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Description

Multiple transcript variants encoding different isoforms have been found for this gene| but the biological validity of some variants has not been determined

Has palmitoyltransferase activity towards HRAS and LCK

The protein forms homo- or heterodimers with other transcription factors of the T-box family or other transcription factors

This gene is localized in the tumor-suppressor gene region and thus it is a candidate gene for malignancies

Axl Polyclonal Antibody, 50ul[BT-AP00783] Peptide Synthesis Multiple transcript variants encoding differentThe protein encoded by AXL (AXL receptor tyrosine kinase) is a member of the Tyro3 Axl Mer (TAM) receptor tyrosine kinase subfamily. The encoded protein possesses an extracellular domain which is composed of two immunoglobulin like motifs at the N terminal, followed by two fibronectin type III motifs. It transduces signals from the extracellular matrix into the cytoplasm by binding to the vitamin K dependent protein growth arrest specific 6 (Gas6).

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