CLIC5 Rabbit Polyclonal Antibody, 100ul Plasmid Preparation The encoded protein inhibits osteoclast

The encoded protein inhibits osteoclast formation and contains a transmembrane domain near the N-terminus as well as the C-type lectin-like extracellular domain

This suggests that members of this family are clearly different from other small GTPases proteins

generating functional redundancy in the pathways that regulate actin cytoskeletal remodeling

which are binding partners to the RAB5 small GTPases

CLIC5 Rabbit Polyclonal Antibody, 100ul Plasmid Preparation The encoded protein inhibits osteoclastThis gene encodes a member of the chloride intracellular channel (CLIC) family of chloride ion channels. The encoded protein associates with actin based cytoskeletal structures and may play a role in multiple processes including hair cell stereocilia formation myoblast proliferation and glomerular podocyte and endothelial cell maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.