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Brn-3 Polyclonal Antibody, 20ul Organelle Studies also called triple-A syndrome or

SKU: 26532076450

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Brn-3 Polyclonal Antibody, 20ul Organelle Studies also called triple-A syndrome orPOU4F3 (POU class 4 homeobox 3) encodes a member of the POU domain family of transcription factors. POU domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in POU4F3 are the cause of non syndromic sensorineural deafness autosomal dominant type 15.

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Description

also called triple-A syndrome or Allgrove syndrome

Screw seal cap design applied

suggesting additional roles for the encoded protein in the metabolism of xenobiotic compounds and the regulation of neurogenesis

and directly interacts with the tumor suppressor p53 to reduce p53 transcriptional activity by reducing p53 protein level in the absence of DNA damage

Brn-3 Polyclonal Antibody, 20ul Organelle Studies also called triple-A syndrome orPOU4F3 (POU class 4 homeobox 3) encodes a member of the POU domain family of transcription factors. POU domain proteins have been observed to play important roles in control of cell identity in several systems. This protein is found in the retina and may play a role in determining or maintaining the identities of a small subset of visual system neurons. Defects in POU4F3 are the cause of non syndromic sensorineural deafness autosomal dominant type 15.

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